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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4205bb522fe16cdc50952a7017d80f8f196f236a06d15d5f0485f85c1d03f199' 
  AND token = 'ww/Kki4rlQylSDh/1A9VUDy83DUf04guTgtW0Vk7nVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}