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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b00dd6d6002ae1062b5305f74809571b4a7d6b5ffc5352786da0b7190083b6af' 
  AND token = 'YX9SbnZ2Ek1Js3iYVEVP8PGv+CulsOdg63sr0vfWFco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}