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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fcef8b4f863a4bfa6eb6ccba86d850f148552be0f0a81ffb3ccda365165f8cb' 
  AND token = 'eXGRxqjcCWcQck4fzOD3zdK6EsMROTZA8BIOxOPDQdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}