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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06aca862d51a5dd91c90bcb4ad46dea2c010c2b90c28f368fe4222fd3f8f2374' 
  AND token = 'QSfE8wquXF6WTefgAPvjgKGI4dvXvC7LBRsV2UwfRuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}