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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5506a318d7029f3d5f7004d10871e624d63d5410b2fec02d2bd56f0db4bd5d6e' 
  AND token = 'IlIusKZ608Oyf8Q+riNjKyFUOO//eoBhl4xgpdfIUHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}