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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743683bad3bb82590910822198058f2829f0ddf9ebb73b98412da165ab81bb38' 
  AND token = '9dnsAC4zGtxRJsUf+mc4F7iSCbmXSf3/NZZW+R/ZOMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}