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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3b080d33ce72f07118db1adb461176d3c1f0da2fe868b3131e43f342d9bd522' 
  AND token = '2Gc3t36AvlMiZC4a1ujRmkZcKNQC/Bf8Mg6+zD8sQK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}