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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4b1955473fe04d80193d5c101ba221abcc631a79e9d6a1c5517b326994e815b' 
  AND token = 'p2os7XroWyMWTLqrccjDzMWszTTWelkKGb0jBGBdqDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}