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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50fd6dea3c37b64b952b68f9edc01f9630866f62e6b66b0daddc7cb25927bf10' 
  AND token = 'qykLnH5+icMC8LPbT00Ti/9mq10xVPUQHbpkRKTzGj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}