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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8177a9c5e9d78a9861430d266f8d7276be1309dd046fbf6fd1c6a8ee916b828c' 
  AND token = 'KThyw2fW9RTE0ZxqTwciR75m3HsoqZ/7itZ+3Orqyr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}