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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec8672640da82e13caa74017ce62db0feebffcc51d35dabb51cc242dff45ada6' 
  AND token = 'vVIUGJqACvo6A5S/Iv0PGdRDnYdUiGue6mz4CzPm1DU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}