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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '482afeb56bfce04a6384a7b8f704b1596e3a398539ac2a5a107ba145581aa6a4' 
  AND token = 'f5piDmobkEGt7E5fMHvPTE6+5/g/szv+R7Kdb4jz6vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}