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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2865191fe5e2c3204e4ae739f13dde6fdef233dab29ee74c1c77c48aa3d23e53' 
  AND token = 'zb17eCt4/uI2k7bybxPq34lqm/sCXjR5LhQi9hQ/584=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}