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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cc2efba51c39bc0be369a2017e2fbee9a4b433bd5bb13d6070c770e815103f7' 
  AND token = 'zsWZF2uAyEIii2tco8RH/5R+APhHe2Zk8WftbOH1eG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}