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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcff25224251c44e850ebb58036a2761645c4ebe33d2ff90f8825b7d7f860309' 
  AND token = 'ExUGW10u5Axz4QgwVpbtgnjMaCUEpRYKRzne6BCtaa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}