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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c3aafe971c3f4080041c14878cbb1074a5b6ad7abc0d6397091446f27bd8e26' 
  AND token = 'kDJLr1RWgWJTh6M2JN9ZghlmpmlQOj8GcDNtceFDy/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}