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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '370326026c2c34b1b01e91fff1dd7d25dd978e715eb173a071586e4bb2c97f03' 
  AND token = 'wti+iLdz0z7z/Xvy9mM7//I7nFIYtkqmYAv0phfXC3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}