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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c51d1a1f7056d7f33d713735f1e8f1f37f4f84225d100e89c3091d182a8454f5' 
  AND token = 'e8c/NZDL7w00aujCriKUFkmtpFXnp94ncQuVGDDtmrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}