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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3b6be2beb2dbd649c6ef5e1f6bc115dbd9898f11574c4623f65bd920801aec0' 
  AND token = 'cV1Td6UyF2LVHKvLV5Hm5/FmWngI+XRdlU4/lYMs0G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}