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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15416c0cfde6f533eca3a20ce48c74cef080c67bd41cb11024366e6404a10d43' 
  AND token = 'OXWyntX3nCI34MPQHZB7BRuUI0wAz/3rQNoDpg7SVd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}