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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f811b6a80aeb414e41a30b05afe12caee1bc16b1ed254c878299542cf29ce360' 
  AND token = 'pKH313jgBqKvLgqDoRLAIKzwWlMk80otJ/KuHeUpUho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}