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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e64686abd5d06adf78c889e9a356b144720b16e7d68f2ffce6bcaf2400d8e78' 
  AND token = 'Fx0x15j1drls8qy6/67psF2tzDIcRulqVuhlZU7jDJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}