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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '378e60938a1ef232d85e8f508b714105077f4344cfc9cbd0ae4f4a3754e8c3f3' 
  AND token = 'hZh4MdMyWYQ5Mhdlkg8Ufv02rMn4s/ZI1f+uPrHhD7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}