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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e6e406a1aaa6173e05bee0112acc16628fd72b14dde5b8255d78d26c0f459eb' 
  AND token = 'QBgWyR+9aio2EYf0fgVidEMLzHBP0sOg6Xgiogd3f94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}