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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abb060b492e509a7a7eadfc460a0e4a0b4307cce354e2b504821b7f24539e2be' 
  AND token = '0uY8Z+rXoIGTd43r4P255mUMw77L9gjJ3gv3QLRdugY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}