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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d966ad555ef599489adc2e26d60c8efcf50fa5a78b8fa46e1e7be53b1e1ab8e' 
  AND token = 'wqYql32Ca4cu1vG8YHlks6UFHSkVnvsLcDp0dMMIcnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}