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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5eed5d5f4d6932c7704fc9995e507d7259270438e7b4685bacbf7bcf43003df' 
  AND token = 'NmeOt4ewlH4TXBYNZOm9LMUkOXUCGfQeyT2nWqfcPpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}