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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e0a192e44ef5feb833d7875ac127b04a9583d04d76548508100bb0b44e237c' 
  AND token = '4fO8dF4GebUAXd6ULsD1+QujkaUhVqHvtbUKFlyFjHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}