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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f4f8a39f01af96bfb31fd5d7b67f0900851e074bb9bf34c64428cf6ffba3a24' 
  AND token = '3Ss+SmCfXvSItIrig3Fwe8+zLPOI08VJcYX/vGvtFa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}