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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a866e260549ad1c7227e97f537a67b273579c8e307e64c473ce9b1ecb90de88b' 
  AND token = 't/nWwi723j7Te038Imv7K4qxwEV7otMv8p/tZsLj3JQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}