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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c245e6fa6797618db8481f7fc14f9f48d1108d022d8eb78b91abd44067af20e0' 
  AND token = 'OrCXcf1xBGlbET3Fr9g5OrHSwpp9tziBZ9MG5FR4czQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}