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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76e61fa4cbd8e12b75f384564c3d44257a854e56e5ea293e5f49d3aeb0a86b60' 
  AND token = '6FipDr1Xqf2VY9NN9DpdPcOZTuT2Vp5f36PCSZ1MIXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}