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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5543ff2c7152ebf701dd5bbe94175ed81a835be351e38ddcf0c19f677d6274f1' 
  AND token = '3Sio6hCsfkxJLWH0t85NZ4nwebIbu0U7EYYpN0xba0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}