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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b99ee3b6c9f76c1f43563bed21cb84973e97a718f797910299702c7233a9f712' 
  AND token = 'zYq1Oo/f1cur22rTKo2JDhYIArOtjtrPoSdG4Sqtfoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}