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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68eeb720cb3ae053ca99600f6b175e71456de6f2f44189eda6003f671a11067d' 
  AND token = 'DgU+nyqQ0J6t/YlifWkUTw4KOtntbFu4JD0t3bmq0Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}