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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b9c498b343a7555bc507b32024a76408f67b954e90b780d8bab3eb9cff34778' 
  AND token = '8XHXZ1zGOjjjiFQnUPqgQjAON2tQS2ihyb+4C8aKtIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}