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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0adddb6e8b2000981d7cc915974d653f5b6501ac146e370884bb067675ede68a' 
  AND token = 'p2kUalWr2LcejCfC+O0iTPj7QGLZOO/39WcfFsmj3O8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}