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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '181a4d59d202c658f3d031acbba212f4850a48758a9a690d4d4c71199226c38c' 
  AND token = '5fSF7KEMi6mi2mHPSxxFzWZ1PGQqfuT1wz1uH0Q8H7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}