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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9a6cba5f478d724a00b375c06818934a0e289d6187f48bcfbdb0df6e86e80d1' 
  AND token = 'Oqtcsx1uSSDEjZ/mfNPEY5AzRY5dU5MbIDh5/LZXrXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}