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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc1187591ad4ca30c45ac25603f8e6511f7619cc2fb74d34d2e726c5706d3d12' 
  AND token = 'DWn+YBniugqjFay89sWbbmTO+IKceMMycQuvaZvDxd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}