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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e6fe321a72a43f09c91c24b9a9af6fa4dbf962bbb89b5d8b68aabfebda01e2' 
  AND token = 'YxBSExMZT660NIozpYhVymMYEUxIMyAdaoiehKX+mI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}