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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e121500b9092b2b7a0a563f9caf1946791152e1aa04702a8e47b4c5c3a3618' 
  AND token = 'n8+c8y3Cr/ptMU+bYWD1ohBcyTIbGXCjIomQFAidc20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}