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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e46f391fbe334a12a315d21b1c09a86b8cd8b17ecd36c125c3d29de4a7cc260' 
  AND token = 'td3HFTziG550nkMOL6QxNA6iOW1syM71jpOnE1F/sCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}