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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ae364cc46ccbb6a1c7b780502a1ec1ba2c1c46a359c69e2464502698b9be9e5' 
  AND token = '1ZomZxVZtdjTHinlRctNJc9D3SPYsIkoWsgnJR7WYsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}