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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '688b753289c61686180b178050c060f4ac0dbaec7fe955760c07fbecd9c6c4e2' 
  AND token = 'JIpz/iLHiv24U0LwF4WvedvNFCOeyGFF3DBrlxGXL5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}