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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8d0f43f46036921c1efc343f4841c5b9bbb1aa356f952837af9f809cc04562b' 
  AND token = 'CxCoCUYZMz63gmY2V9VJs+fftO7LkBd9x3y2Dmu7JBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}