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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d0caee2b446178ddb7ef80675dbb0fba9d7eddfb883cc961184bc4b5c7f9a60' 
  AND token = 'DZx+T9DLikY3O0pV25FxZ1Ff3GIM3eKQ0F7xjedGcto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}