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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97b484a3b5cfc25a25ef142783b05a4301d97326fb90251d8fe34aaa6c457f42' 
  AND token = 'InC6x4w6/FfrEi4P0RSWlOZ/hwMVocR6lPfRxRNPwGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}