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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a3d492e0b969e970a158406d0fd715d5e8646c1051ef0cd69a2cd2558ef279e' 
  AND token = 'x5jdUbqysW+lNHDSlzOaBMda6In28ylyTLEeVwqg7fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}