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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce6a71b89fb9148103611e0d3050359be4ee47af20d9a0b6651343335e97f523' 
  AND token = '8bSbsNWseF0UdTJinr8vFhTrh9IeaeUCeBv6LjLUQv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}